Comparison of antibiotic therapy in complicated appendicitis in pediatrics. Preliminary report (in Spanish)

Abstract

Introduction. Acute appendicitis is the most frequent surgical pathology in pediatrics and requires adequate management with antibiotics postoperatively, especially in the complicated phase of the disease. Objective. To compare the triple antibiotic therapy scheme vs a double scheme used in patients postoperative on in our unit. Materials and methods. Prospective study of the Pediatric Surgery Unit of the Carlos Andrade Marin Specialties Hospital, which included a total of 90 patients operated on for complicated appendicitis, of whom 55 received ampicillin + metronidazole + gentamicin and 35 ceftriaxone + metronidazole. The variables of hospital stay, complications and cost of each scheme were compared. Results. There were no significant differences between the two groups of patients in relation to the analyzed variables. Conclusions. No statistically significant differences were found between both schemes in this preliminary report, with the difference that with the triple scheme the frequency of administration is lower and exposure to the side effects of aminoglycosides is avoided.